Lee Lab

Research

Take a glimpse at the variety of biophysical chemistry research we conduct in our lab! We are always looking for collaborations, new techniques to address our biological problems, and new applications for techniques we’ve developed. Swipe through to see examples of projects both ongoing and old (but open!) and click Read More to dive deeper!

 

Understanding alpha-Synuclein-Membrane Interactions

We utilize multiple experimental biophysics techniques to probe alpha-Synuclein membrane binding and sensitivity!

Lipids in Immunity

We are working to uncover the mechanisms behind lipid recognition in peripheral immunological proteins using X-ray reflectivity, MD simulations, and more.

Lung Surfactant

We use our home built Langmuir trough to explore lipid monolayers and model lung surfactants in various conditions.

Soft Matter

In collaboration with the SurgBioMech Lab, we characterize soft matter thin sheet systems under external forces to model their responses, including lipid monolayers.

Free Energy Calculations

Combining computational and experimental research, we calculate the binding free energies of peripheral membrane-binding proteins.

Myelin Formation

Past research (and an open project) involved using atomic force microscopy to characterize myelin tubule interactions with supported lipid bilayers.

Antimicrobial Peptides

Past research (and an open project) involved using fluorescence and atomic force microscopy to characterize how antimicrobial peptides disrupt lipid membranes.

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